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Charité - Movement Disorders & Neuromodulation Unit at the Neurology Department Charité Universitätsmedizin Berlin (Campus Mitte)

Data Scientist / Tech Student For Neuroscience

English

Classification and prediction of hyperkinetic movement in Parkinson’s disease patients
with a novel magneto-encephalography method (OPM-MEG)

Working field:

Neuroscience
Write your master thesis in combination with a student job at our new project:

  • Collaborative project between the Movement Disorders & Neuromodulation Unit at the Neurology
    Department Charité Campus Mitte and the MEG Research Group at the
    Physikalisch-Technische Bundesanstalt (PTB) Berlin
  • Dyskinesia are abnormal, involuntary movements and are a common side effect of common
    medication in Parkinson’s disease
  • Project aim 1: Understanding cortical neurophysiology within the development of treatment-
    induced dyskinesia in Parkinson patients.
  • Project aim 2: Predicting dyskinetic states in both movement absence and movement
    presence based on cortical features extracted from OPM-MEG data.
  • Patients will be recorded with a novel magneto-encephalography method (optically-pumped
    magnetometers, OPM-MEG), combined with kinematic analysis and clinical assessments.

Requirements:

Your project tasks:

  • Gain knowledge on neurophysiology (especially OPM-MEG) and Parkinson’s disease
  • Develop workflow to pre-process OPM-MEG data, using available open-source packages (i.e.,
    MNE python)
  • Develop workflow to combine OPM-MEG data with individual neuro-anatomy (MRI)
  • Extract spectral features per cortical region and characterize and classify movements and
    dyskinetic states using machine learning methods
  • Code development preferably in Python

Requirements:

  • At least basic experience in Python programming
  • Interest in computational neuroscience
  • Advanced English, as we are an international research group (but direct supervisors speak German)

What we offer:

  • Dedicated post-doctoral supervision regarding neuroscience, neurophysiology, machine learning,
    programming, and project management
  • Flat hierarchies and a safe and supportive research atmosphere
  • Working space at Charité Campus Mitte
  • Being part of inter-regional Research Collaboration ReTune and it’s educational activities
  • Part-time appointment as “Hi-Wi” (€ 13 / hour, 40 – 60 hours per month) for 6 months
  • Results and Methods will be used for scientific publication(s)
    No guarantee on project finishing timelines, co-authorship possible.

How to apply:

Send your questions or directly apply by sending your motivation letter and CV to both of us:
Dr.-Ing. Christina Salchow-Hömmen: christina.salchow@charite.de
and
Jeroen Habets, MD PhD: jeroen.habets@charite.de